How Does Laser Therapy Work?

PN_Socks.JPG  Laser therapy is recognized as an approved treatment by the FDA for several types of peripheral neuropathy.

Here is the information I have gathered on low level laser and LEDs and their benefit on healing  neuropathy:

  1. The LEDs at specific wavelengths are reported to increase circulation by increasing the formation of new capillaries. New capillaries speed up the healing process by carrying more oxygen as well as more nutrients needed for healing and they can also carry more waste products away.
  2. Collagen is the most common protein found in the body and the essential protein used to repair damaged tissue and to replace old tissue. Studies cite that LEDs stimulate the production of collagen. It has been reported that by increasing collagen production, less scar tissue is formed at the damaged site.
  3. LED therapy is reported to stimulate the release of adenosine triphosphate (ATP). ATP is the major carrier of energy to all cells and provides the chemical energy that drives the chemical reaction of the cell. Increases in ATP allow cells to use nutrients faster and get rid of waste products faster by increasing the energy level in the cell.
  4. Increases lymphatic system activity. Edema has two basic components, liquid and protein. Research has shown that the lymph vessel diameter and the flow of the lymph system can be doubled with the use of light therapy. This means that both parts of edema can be eliminated at a much faster rate to relieve swelling.
  5. Reduces the excitability of nervous tissue. The light energy stimulates the release of endorphins which are the body's own long term pain fighting chemicals.
  6. May improve peripheral neuropathies by stimulating nitric oxide production.
  7. Increases RNA and DNA synthesis which helps damaged cells to be replaced more quickly.
  8. Increases the process of scavenging for and ingesting dead or degenerated cells by phagocyte cells for the purpose of clean up. This is an important part of the infection fighting process. Destruction of the infection and clean up must occur before the healing process can take place.
  9. Stimulates fibroblastic activity that aids in the repair process. Fibroblasts are present in connective tissue and are capable of forming collagen fibers.*
  10. Stimulates tissue granulation and connective tissue projections, part of the healing process.
  11. Stimulates trigger and acupuncture points.
  12. Helps relax muscles.

Sources:
  1. Lasers in Surgery and Medicine 9:1-5, Mayo Clinic, Rochester, Minnesota, 1989).
  2. Journal of Clinical Laser Medicine & Surgery Polychromatic LED Therapy in Burn Healing of Non-diabetic and Diabetic Rats
  3. 2 Impaired Wound Healing and angiogenesis in eNOS-deficient Mice, PC Lee; American Journal of Physiology , 1999 October,277 (4 Pt 2):H1600-8
  4. Oct 2003, Vol. 21, No. 5 : 249 -258 
  5. 3May 2006 Issue Of Acta Diabetologica
  6. Biofizika. 2006 Mar-Apr; 51(2):332-9
  7. The results obtained show that exposure of wounds to both laser and light-emitting diode irradiation causes a decrease in the oxidative stress in the rat wound fluid. No significant quantitative difference between the effects of laser and light-emitting diode irradiation was found.*Department of Rehabilitation Sciences and Physiotherapy, Ghent University, 9000 Ghent, Belgium. 2003;18(2):95-9
  8. Mitochondrial signal transduction in accelerated wound and retinal healing by near-infrared light therapy.
  9. Mitochondrion. 2004 Sep;4(5-6):559-67. 
  10. PMID: 16120414 [PubMed]
  11. Mitochondrion. 2004 Sep;4(5-6):559-67. 
  12. PMID: 16120414 [PubMed]
  13. Photomedicine and Laser Surgery
  14. Polarized Light (400–2000 nm) and Non-ablative Laser (685 nm): A Description of the Wound Healing Process Using Immunohistochemical Analysis
  15. Oct 2005, Vol. 23, No. 5 : 485 -492 
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